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William Hogan MD, MS
William Hogan, MD, MS

William Hogan, MD, MS

Mary T. and Ted D. Kellner Chair of Data Science; Director, Data Science Institute; Professor, Data Science Institute; Associate Director for Data Science, Mellowes Center for Genomic and Precision Medicine

Locations

  • DSI
  • TBRC C4166

    Secondary Appointment: Department of Medicine

Contact Information

Education

BS, Pennsylvania State University
MD, Medicine, Jefferson Medical College
MS, Intelligent Systems, University of Pittsburg

Biography

Dr. Hogan is professor and the founding director of the Data Science Institute. He has over 20 years experience in biomedical data science and informatics, including numerous leadership roles and accomplishments in building large-scale infrastructure, creating and implementing public health surveillance systems, developing and disseminating data standards, designing and validating artificial intelligence models, and innovating analysis methods. He has also created graduate programs in biomedical data science and informatics from the ground up, with their PhD graduates moving on to post-doctoral fellowships and faculty positions at multiple institutions. He has served as research mentor to over 20 junior faculty, post-doctoral fellows, and MS and PhD students. Over the years, he has been principal investigator or co-investigator on over $100M in grant funding, including major infrastructure grants that include as a core component the transformation of electronic health record data into a research-ready resource for observational and comparative effectiveness studies, pragmatic trials, disease surveillance, and cohort discovery for enrollment in trials. He has authored over 150 peer-reviewed publications describing this work. His core area of interest is biomedical ontology, or how to represent the types of things that are objects of study in healthcare and biomedical science in order to ensure that data are reusable and that information systems are interoperable. He is the creator and lead curator of three, major ontologies in the Open Biological and Biomedical Ontology (OBO) Foundry: the Drug Ontology, the Ontology of Medically Relevant Social Entities, and the Apollo-SV ontology. All three ontologies rank in the top 20% of OBO ontologies in terms of re-use by other OBO ontologies. He serves on the OBO Foundry Operations Committee and its Editorial Working Group.

Publications

  • (Loftus TJ, Ruppert MM, Shickel B, Ozrazgat-Baslanti T, Balch JA, Abbott KL, Hu D, Javed A, Madbak F, Guirgis F, Skarupa D, Efron PA, Tighe PJ, Hogan WR, Rashidi P, Upchurch GR Jr, Bihorac A.) Ann Surg Open. 2024 Jun;5(2):e429 PMID: 38911666 PMCID: PMC11191932 06/24/2024

  • (Wagner MM, Hogan WR, Levander JD, Diller M.) J Biomed Inform. 2024 Jun;154:104647 PMID: 38692465 PMCID: PMC11250896 SCOPUS ID: 2-s2.0-85192218312 05/02/2024

  • (Yu Z, Peng C, Yang X, Dang C, Adekkanattu P, Gopal Patra B, Peng Y, Pathak J, Wilson DL, Chang CY, Lo-Ciganic WH, George TJ, Hogan WR, Guo Y, Bian J, Wu Y.) J Biomed Inform. 2024 May;153:104642 PMID: 38621641 PMCID: PMC11141428 SCOPUS ID: 2-s2.0-85190333397 04/16/2024

  • (Lemas DJ, Du X, Rouhizadeh M, Lewis B, Frank S, Wright L, Spirache A, Gonzalez L, Cheves R, Magalhães M, Zapata R, Reddy R, Xu K, Parker L, Harle C, Young B, Louis-Jaques A, Zhang B, Thompson L, Hogan WR, Modave F.) Sci Rep. 2024 Apr 03;14(1):7831 PMID: 38570569 PMCID: PMC10991582 SCOPUS ID: 2-s2.0-85189809672 04/04/2024

  • (Venner E, Patterson K, Kalra D, Wheeler MM, Chen YJ, Kalla SE, Yuan B, Karnes JH, Walker K, Smith JD, McGee S, Radhakrishnan A, Haddad A, Empey PE, Wang Q, Lichtenstein L, Toledo D, Jarvik G, Musick A, Gibbs RA, All of Us Research Program Investigators.) Commun Biol. 2024 Feb 19;7(1):174 PMID: 38374434 PMCID: PMC10876563 SCOPUS ID: 2-s2.0-85185702226 02/20/2024

  • (Smith KM, Keshwani S, Walsh MG, Winterstein AG, Gurka MJ, Libby A, Hogan WR, Pepine CJ, Cooper-DeHoff RM, Smith SM.) Hypertension. 2024 Feb;81(2):e7-e9 PMID: 38232142 PMCID: PMC10795723 SCOPUS ID: 2-s2.0-85182796232 01/17/2024

  • (Varma JK, Zang C, Carton TW, Block JP, Khullar DJ, Zhang Y, Weiner MG, Rothman RL, Schenck EJ, Xu Z, Lyman K, Bian J, Xu J, Shenkman EA, Maughan C, Castro-Baucom L, O'Brien L, Wang F, Kaushal R, RECOVER Consortium.) PLoS One. 2024;19(6):e0282451 PMID: 38843159 PMCID: PMC11156291 SCOPUS ID: 2-s2.0-85195439417 06/06/2024

  • (Ozrazgat-Baslanti T, Ren Y, Adiyeke E, Islam R, Hashemighouchani H, Ruppert M, Miao S, Loftus T, Johnson-Mann C, Madushani RWMA, Shenkman EA, Hogan W, Segal MS, Lipori G, Bihorac A, Hobson C.) PLoS One. 2024;19(4):e0299332 PMID: 38652731 PMCID: PMC11037544 SCOPUS ID: 2-s2.0-85191405922 04/23/2024

  • (Chen A, Zhao Y, Zheng Y, Hu H, Hu X, Fishe JN, Hogan WR, Shenkman EA, Guo Y, Bian J.) Informatics. March 2024;11(1) SCOPUS ID: 2-s2.0-85188969915 03/01/2024

  • (Waitman LR, Bailey LC, Becich MJ, Chung-Bridges K, Dusetzina SB, Espino JU, Hogan WR, Kaushal R, McClay JC, Merritt JG, Rothman RL, Shenkman EA, Song X, Nauman E.) Med Care. 2023 Dec 01;61(12 Suppl 2):S153-S160 PMID: 37963035 PMCID: PMC10635342 SCOPUS ID: 2-s2.0-85177102847 11/14/2023

  • (Peng C, Yang X, Chen A, Smith KE, PourNejatian N, Costa AB, Martin C, Flores MG, Zhang Y, Magoc T, Lipori G, Mitchell DA, Ospina NS, Ahmed MM, Hogan WR, Shenkman EA, Guo Y, Bian J, Wu Y.) NPJ Digit Med. 2023 Nov 16;6(1):210 PMID: 37973919 PMCID: PMC10654385 11/17/2023

  • (Clint Dowland S, Smith B, Diller MA, Landgrebe J, Hogan WR.) Applied Ontology. 7 November 2023;18(3):239-262 SCOPUS ID: 2-s2.0-85177032417 11/07/2023